Here's a breakdown of chromatin vs. nucleosomes:
Nucleosome: A nucleosome is the fundamental repeating unit of <a href="https://www.wikiwhat.page/kavramlar/chromatin">chromatin</a>. It's essentially the first level of DNA organization in eukaryotes. A nucleosome consists of a core of eight histone proteins (two each of H2A, H2B, H3, and H4) around which approximately 146 base pairs of DNA are wrapped. The DNA is held in place by the histone fold domain.
Chromatin: <a href="https://www.wikiwhat.page/kavramlar/chromatin">Chromatin</a> refers to the complex of DNA and proteins (mainly histones) that make up chromosomes within the nucleus of eukaryotic cells. It is the substance of heredity. Think of chromatin as the "packaged" form of DNA. It exists in two main forms:
Relationship: Nucleosomes are the building blocks of <a href="https://www.wikiwhat.page/kavramlar/chromatin">chromatin</a>. Imagine nucleosomes as beads on a string; the "string" is the DNA, and the arrangement and modification of these "beads" (nucleosomes) influence the overall structure and function of the "string" (<a href="https://www.wikiwhat.page/kavramlar/chromatin">chromatin</a>).
Function:
In essence, nucleosomes are a component of <a href="https://www.wikiwhat.page/kavramlar/chromatin">chromatin</a>.
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